Acenocoumarol-Induced Anticoagulant–Related Nephropathy with Newly Diagnosed IgA Nephropathy: a Repeat Biopsy Case Report

نویسندگان

چکیده

Anticoagulant-related nephropathy (ARN) is an underestimated cause of acute kidney injury (AKI) with poor renal and overall prognosis. Pathogenesis not fully elucidated yet, although AKI probably resulting from glomerular hemorrhage most commonly has been described in patients lesions, that alter the permeability, conditions hyperfiltration. Herein, we describe a case 58-year-old man who presented macroscopic hematuria AKI, recently taking acenocoumarol for aortic valve replacement. The first biopsy showed red cell casts tubules, one crescent formation glomeruli mild immunoglobulin A deposition, severe interstitial inflammation. Based on these findings, patient was diagnosed acenocoumarol-induced ARN newly IgA switched to tinzaparin short course corticosteroids. Renal improvement usually partial delayed, as confirmed by second our after 6 months.

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ژورنال

عنوان ژورنال: SN Comprehensive Clinical Medicine

سال: 2022

ISSN: ['2523-8973']

DOI: https://doi.org/10.1007/s42399-022-01173-6